Our lab is interested in understanding the modulation of neuronal signals, which determine emotional and motor behavior. Modulatory signals in the brain are mediated by G protein coupled receptors. These GPCRs are expressed on every cell type in the brain and sense differences in the behavior by converting extracellular cues into intracellular signals. There are more than 350 different family excluding odorant receptors in the brain, which play an important role as therapeutic target. In fact 60% of all FDA approved drugs act on GPCRs.
