Publications
2022
Dithiolopyrrolones are Prochelators that Are Activated by
Glutathione
Albini F, Bormann S, Gerschel P, Ludwig VA, Neumann W
Chem. - J. Eur. 2022
DOI: 10.1002/chem.202202567
Siderophore immunization restricts colonization of adherent-invasive Escherichia coli and ameliorates experimental colitis
Gerner RR, Hossain S, Sargun A, Siada K, Norton G, Zheng T, Neumann W, Nuccio S-P, Nolan EM, Raffatellu M
mBio 2022, e02184-22
DOI: 10.1128/mbio.02184-22
2020
Trends in inorganic chemistry: Bioinorganic and coordination chemistry of the d- and f-block elements 2019
Munz D, Neumann W
Nachr. Chem. 2020, 68, 65–77
DOI: 10.1002/nadc.20204093404
Carboranyl derivatives of rofecoxib with cytostatic activity against human melanoma and colon cancer cells
Buzharevski A, Paskas S, Sárosi MB, Laube M, Lönnecke P, Neumann W, Murganic B, Mijatovic S, Maksimovic-Ivanic D, Pietzsch J, Hey-Hawkins E
Sci. Rep. 2020, 10, 4827
DOI: 10.1038/s41598-020-59059-3
2019
Carboranyl analogues of ketoprofen with cytostatic activity against human melanoma and colon cancer cell lines
Buzharevski A, Paskas S, Laube M, Lönnecke P, Neumann W, Murganic B, Mijatovic S, Maksimovic-Ivanic D, Pietzsch J, Hey-Hawkins E
ACS Omega 2019, 4, 8824–8833
DOI: 10.1021/acsomega.9b00412
Carboranyl analogues of celecoxib with potent cytostatic ability against human melanoma and colon cancer cell lines
Buzharevski A, Paskas S, Sárosi MB, Laube M, Lönnecke P, Neumann W, Mijatovic S, Maksimovic-Ivanic D, Pietzsch J, Hey-Hawkins E
ChemMedChem 2019,14, 315–321
DOI: 10.1002/cmdc.201800685
Studies towards the development of a PET radiotracer for imaging of the P2Y1 receptors in the brain: synthesis, 18F-labeling and preliminary biological evaluation
Moldovan R-P, Wenzel B, Teodoro R, Neumann W, Dukic-Stefanovic S, Kraus W, Rong P, Deuther-Conrad W, Hey-Hawkins E, Krügel U, Brust P
Eur. J. Med. Chem. 2019, 165, 142–159
DOI: 10.1016/j.ejmech.2019.01.006
2018
Evaluation of a reducible disulfide linker for siderophore‑mediated delivery of antibiotics
Neumann W, Nolan EM
J. Inorg. Biol. Chem. 2018, 23, 1025–1036
DOI: 10.1007/s00775-018-1588-y
Design, solid-phase synthesis and evaluation of siderophore analogs for iron delivery into the human pathogen Campylobacter jejuni
Zamora C, Madec A, Neumann W, Nolan EM, Imperiali B
Bioorg. Med. Chem. 2018, 26, 5314–5321
DOI: 10.1016/j.bmc.2018.04.030
Esterase-catalyzed siderophore hydrolysis activates an enterobactin-ciprofloxacin conjugate and confers targeted antibacterial activity
Neumann W, Sassone-Corsi M, Raffatellu M, Nolan EM
J. Am. Chem. Soc. 2018, 140, 5193–5201
DOI: 10.1021/jacs.8b01042
2017
Transition metals at the host–pathogen interface: How Neisseria exploit human metalloproteins for acquiring iron and zinc
Neumann W, Hadley RC, Nolan EM
Essays Biochem. 2017, 61, 211–223
DOI: 10.1042/EBC20160084
Metal homeostasis in infectious disease: Recent advances in bacterial metallophores and the human metal-withholding response
Neumann W, Gulati A, Nolan EM
Curr. Opin. Chem. Biol. 2017, 37, 10–18
DOI: 10.1016/j.cbpa.2016.09.012
Molecular modeling of the interactions between carborane-containing analogs of indomethacin and cyclooxygenase-2
Sárosi MB, Neumann W, Lybrand TP, Hey-Hawkins E
J. Chem. Inf. Model. 2017, 57, 2056–2067
DOI: 10.1021/acs.jcim.7b00113
Carboranes as aryl mimetics in catalysis: A highly active zwitterionic NHC precatalyst
Selg C, Neumann W, Lönnecke P, Hey-Hawkins E, Zeitler K
Chem. Eur. J. 2017, 23, 7932–7937
DOI: 10.1002/chem.201700209
2016
nido-Dicarbaborate induces potent and selective inhibition of cyclooxygenase-2
Neumann W, Xu S, Sárosi MB, Scholz MS, Crews BC, Ghebreselasie K, Banerjee S, Marnett LJ, Hey-Hawkins E
ChemMedChem 2016, 11, 175–178
DOI: 10.1002/cmdc.201500199
2015
Reduction of hydroxy-functionalised carbaboranyl carboxylic acids and ketones by organolithium reagents
Neumann W, Hiller M, Sárosi MB, Lönnecke P, Hey-Hawkins E
Dalton Trans. 2015, 44, 6638–6644
DOI: 10.1039/c5dt00761e
Conjugation of cisplatin analogues and cyclooxygenase inhibitors to overcome cisplatin resistance
Neumann W, Crews BC, Sárosi MB, Daniel CM, Ghebreselasie K, Scholz MS, Marnett LJ, Hey-Hawkins E
ChemMedChem 2015, 10, 183–192
DOI: 10.1002/cmdc.201402353
One-pot synthesis of an indole-substituted 7,8-dicarba-nido-dodecahydroundecaborate(–1)
Neumann W, Frank R, Hey-Hawkins E
Dalton Trans. 2015, 44, 1748–1753
DOI: 10.1039/c4dt03218g
Eucalyptol aus Eukalyptusöl: Eukalyptus – Fluch oder Segen?
Neumann W, Siehl HU, Zeller KP, Berger S, Sicker D
Chem. Unserer Zeit 2015, 49, 172–181
DOI: 10.1002/ciuz.201500711
2014
Conjugates of cisplatin and cyclooxygenase inhibitors as potent antitumor agents overcoming cisplatin resistance
Neumann W, Crews BC, Marnett LJ, Hey-Hawkins E
ChemMedChem 2014, 9, 1150–1153
DOI: 10.1002/cmdc.201402074
Reduction of hydroxy-functionalised carbaboranyl carboxylic acids to tertiary alcohols by organolithium reagents
Neumann W, Hiller M, Lönnecke P, Hey-Hawkins E
Dalton Trans. 2014, 43, 4935–4937
DOI: 10.1039/c3dt52826j
2013
2-Carbaborane-3-phenyl-1H-indoles – Synthesis via McMurry reaction and cyclooxygenase (COX) inhibition activity
Laube M, Neumann W, Scholz M, Lönnecke P, Crews B, Marnett LJ, Pietzsch J, Kniess T, Hey-Hawkins E
ChemMedChem 2013, 8, 329–335
DOI: 10.1002/cmdc.201200455
Book Chapters
Elementares – Die Spielwiese der Anorganischen Chemie
Albert B, Geelhaar T, Neumann W, Reller A
in Lindhorst TK, Quadbeck-Seeger H-J, GDCh (eds.): Unendliche Weiten. Kreuz und quer durchs Chemie-Universum, Wiley-VCH, Weinheim, 2017
ISBN: 978-3-527-34203-7