Publications

Publications

Manahan-Vaughan D (2010)
MicroRNAs contribute to LTP in the hippocampus in vivo (Commentary on Wibrand et al.).
Eur J Neurosci. 31(4):634-5.

Hagena H, Manahan-Vaughan D (2010)
Frequency facilitation at mossy fiber-CA3 synapses of freely behaving rats contributes to the induction of persistent LTD via an adenosine-A1 receptor-regulated mechanism.
Cereb Cortex 20(5):1121-30.

Tsanov M, Manahan-Vaughan D (2009)
Visual cortex plasticity evokes excitatory alterations in the hippocampus.
Front Integr Neurosci. 3:32.

Tsanov M, Manahan-Vaughan D (2009)
Synaptic plasticity in the adult visual cortex is regulated by the metabotropic glutamate receptor, mGLUR5.
Exp Brain Res. 2009 Aug 12. [Epub ahead of print]

Lemon N, Abidin-Aydin S, Funke K, Manahan-Vaughan D (2009)
Locus coeruleus activation facilitates memory encoding and induces hippocampal LTD that depend on beta-adrenergic receptor activation.
Cerebral Cortex 19(12):2827-37.

Tsanov M, Manahan-Vaughan D (2009)
Long-term plasticity is proportional to theta-activity.
PLoS One, 4(6):e5850.

Stricker S, Manahan-Vaughan D. (2009)
Regulation of long-term depression by increases in [guanosine 3',5'-cyclic monophosphate] in the hippocampal CA1 region of freely behaving rats.
Neuroscience. 158(1): 159-66.

Davanger S, Manahan-Vaughan D, Mulle C, Storm-Mathisen J, Ottersen OP. (2009)
Protein trafficking, targeting, and interaction at the glutamate synapse.
Neuroscience. 158(1): 1-3.

Altinbilek B, Manahan-Vaughan D. (2009)
A specific role for group II metabotropic glutamate receptors in hippocampal long-term depression and spatial memory.
Neuroscience. 158(1):149-158.

Manahan-Vaughan D, Wildförster V, Thomsen C. (2008)
Rescue of hippocampal LTP and learning deficits in a rat model of psychosis by inhibition of glycine transporter-1 (GlyT1).
Eur J Neurosci. 28(7):1342-50.

Bikbaev A, Manahan-Vaughan D. (2008)
Relationship of hippocampal theta and gamma oscillations to potentiation of synaptic transmission.
Front Neurosci. 2:56-63.

Tsanov M, Manahan-Vaughan D. (2008)
Synaptic plasticity from visual cortex to hippocampus: systems integration in spatial information processing.
Neuroscientist. 14(6):584-97.

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Bikbaev A, Neyman S, Ngomba RT, Conn J, Nicoletti F, Manahan-Vaughan D. (2008)
MGluR5 mediates the interaction between late-LTP, network activity, and learning.
PLoS ONE. 3(5):e2155.

Klausnitzer J, Manahan-Vaughan D. (2008)
Frequency facilitation at mossy fiber-CA3 synapses of freely behaving rats is regulated by adenosine A1 receptors.
J Neurosci. 28(18):4836-40

Neyman S, Manahan-Vaughan D. (2008)
Metabotropic glutamate receptor 1 (mGluR1) and 5 (mGluR5) regulate late phases of LTP and LTD in the hippocampal CA1 region in vitro.
Eur J Neurosci. 27(6):1345-52.

Kemp A, Manahan-Vaughan D. (2008)
The hippocampal CA1 region and dentate gyrus differentiate between environmental and spatial feature encoding through long-term depression.
Cereb Cortex. 18(4):968-77. Epub 2007 Aug 16.

Kulla A, Manahan-Vaughan D. (2008)
Modulation by group 1 metabotropic glutamate receptors of depotentiation in the dentate gyrus of freely moving rats.
Hippocampus. 18(1):48-54.

Manahan-Vaughan D, von Haebler D, Winter C, Juckel G, Heinemann U. (2008)
A single application of MK801 causes symptoms of acute psychosis, deficits in spatial memory, and impairment of synaptic plasticity in rats.
Hippocampus. 18(2):125-34.

Kemp A, Manahan-Vaughan D. (2008)
Beta-adrenoreceptors comprise a critical element in learning-facilitated long-term plasticity.
Cereb Cortex. 18(6):1326-34.

Bikbaev A, Manahan-Vaughan D. (2007)
Hippocampal Network Activity is Transiently Altered by Induction of Long-Term Potentiation in the Dentate Gyrus of Freely Behaving Rats.
Front Behav Neurosci. 2007;1:7

Wöhrl R, Eisenach S, Manahan-Vaughan D, Heinemann U, von Haebler D. (2007)
Acute and long-term effects of MK-801 on direct cortical input evoked homosynaptic and heterosynaptic plasticity in the CA1 region of the female rat.
Eur J Neurosci. 26(10):2873-83.

Altinbilek B, Manahan-Vaughan D. (2007)
Antagonism of group III metabotropic glutamate receptors results in impairment of LTD but not LTP in the hippocampal CA1 region, and prevents long-term spatial memory.
Eur J Neurosci. 26(5):1166-72.

Tsanov M, Manahan-Vaughan D. (2007)
Intrinsic, light-independent and visual activity-dependent mechanisms cooperate in the shaping of the field response in rat visual cortex.
J Neurosci. 27(31):8422-9.

Tsanov M, Manahan-Vaughan D. (2007)
The adult visual cortex expresses dynamic synaptic plasticity that is driven by the light/dark cycle.
J Neurosci. 27(31):8414-21.

Naie K, Tsanov M, Manahan-Vaughan D. (2007)
Group I metabotropic glutamate receptors enable two distinct forms of long-term depression in the rat dentate gyrus in vivo.
Eur J Neurosci. 25(11):3264-75.

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Kemp A, Manahan-Vaughan D (2007)
Hippocampal long-term depression: master or minion of declarative memory processes.
Trends Neurosci. 30(3):111-8.

Poschel B, Manahan-Vaughan D. (2007)
Persistent (>24h) long-term depression in the dentate gyrus of freely moving rats is not dependent on activation of NMDA receptors, L-type voltage-gated calcium channels or protein synthesis.
Neuropharmacology. 52:46-54

Lemon N, Manahan-Vaughan D. (2006)
Dopamine D1/D5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depression.
J Neurosci. 26(29):7723-7729.

Naie K, Gundimi S, Siegmund H, Heinemann U, Manahan-Vaughan D. (2006)
Group III metabotropic glutamate receptor-mediated, chemically induced long-term depression differentially affects cell viability in the hippocampus.
Eur J Pharmacol. 535(1-3):104-13.

Zhang L, Kirschstein T, Sommersberg B, Merkens M, Manahan-Vaughan D, Elgersma Y, Beck H. (2005)
Hippocampal synaptic metaplasticity requires inhibitory autophosphorylation of Ca2+/calmodulin-dependent kinase II.
J Neurosci. 25:7697-707

Poschel B, Manahan-Vaughan D. (2005)
Group II mGluR-induced long term depression in the dentate gyrus in vivo is NMDA receptor-independent and does not require protein synthesis.
Neuropharmacology. 49 Suppl 1:1-12.

Naie K, Manahan-Vaughan D. (2005)
Investigations of the protein synthesis dependency of mGluR-induced long-term depression in the dentate gyrus of freely moving rats.
Neuropharmacology. 49 Suppl 1:35-44.

Manahan-Vaughan D, Braunewell KH. (2005)
The metabotropic glutamate receptor, mGluR5, is a key determinant of good and bad spatial learning performance and hippocampal synaptic plasticity.
Cereb Cortex. 15:1703-13.

Naie K, Manahan-Vaughan D. (2005)
Pharmacological antagonism of metabotropic glutamate receptor 1 regulates long-term potentiation and spatial reference memory in the dentate gyrus of freely moving rats via N-methyl-D-aspartate and metabotropic glutamate receptor-dependent mechanisms.
Eur J Neurosci. 21:411-21.

Poschel B, Wroblewska B, Heinemann U, Manahan-Vaughan D. (2005)
The metabotropic glutamate receptor mGluR3 is critically required for hippocampal long-term depression and modulates long-term potentiation in the dentate gyrus of freely moving rats.
Cereb Cortex. 15:1414-23.

Kemp A, Manahan-Vaughan D. (2005)
The 5-hydroxytryptamine4 receptor exhibits frequency-dependent properties in synaptic plasticity and behavioural metaplasticity in the hippocampal CA1 region in vivo.
Cereb Cortex. 15:1037-43.

Brackmann M, Zhao C, Kuhl D, Manahan-Vaughan D, Braunewell KH. (2004)
MGluRs regulate the expression of neuronal calcium sensor proteins NCS-1 and VILIP-1 and the immediate early gene arg3.1/arc in the hippocampus in vivo.
Biochem Biophys Res Commun. 322:1073-9.

Kemp A, Manahan-Vaughan D. (2004)
Hippocampal long-term depression and long-term potentiation encode different aspects of novelty acquisition.
Proc Natl Acad Sci U S A. 101:8192-7.

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Klausnitzer J, Kulla A, Manahan-Vaughan D. (2004)
Role of the group III metabotropic glutamate receptor in LTP, depotentiation and LTD in dentate gyrus of freely moving rats.
Neuropharmacology. 46(2):160-70.

Solger J, Wozny C, Manahan-Vaughan D, Behr J. (2004)
Distinct mechanisms of bidirectional activity-dependent synaptic plasticity in superficial and deep layers of rat entorhinal cortex.
Eur J Neurosci. 19:2003-7.

Blandini F, Braunewell KH, Manahan-Vaughan D, Orzi F, Sarti P. (2004)
Neurodegeneration and energy metabolism.
Cell Death Differ. 11:479-84.

Naie K, Manahan-Vaughan D. (2004)
Regulation by metabotropic glutamate receptor 5 of LTP in the dentate gyrus of freely moving rats: relevance for learning and memory formation.
Cereb Cortex. 14:189-98.

Braunewell KH, Brackmann M, Manahan-Vaughan D. (2003)
Group I mGlu receptors regulate the expression of the neuronal calcium sensor protein VILIP-1 in vitro and in vivo: implications for mGlu receptor-dependent hippocampal plasticity?
Neuropharmacology. 44:707-15.

Manahan-Vaughan D, Ngomba RT, Storto M, Kulla A, Catania MV, Chiechio S, Rampello L, Passarelli F, Capece A, Reymann KG, Nicoletti F. (2003)
An increased expression of the mGlu5 receptor protein following LTP induction at the perforant path-dentate gyrus synapse in freely moving rats.
Neuropharmacology. 44(1):17-25.

Manahan-Vaughan D, Kulla A. (2003)
Regulation of depotentiation and long-term potentiation in the dentate gyrus of freely moving rats by dopamine D2-like receptors.
Cereb Cortex. 13(2):123-35.

Kulla A, Manahan-Vaughan D. (2002)
Modulation by serotonin 5-HT(4) receptors of long-term potentiation and depotentiation in the dentate gyrus of freely moving rats.
Cereb Cortex. 12(2):150-62.

Braunewell KH, Manahan-Vaughan D. (2001)
Long-term depression: a cellular basis for learning?
Rev Neurosci. 12:121-40.

Manahan-Vaughan, D., Kulla, A. and Frey J.U. (2000)
Requirement of translation but not transcription for the maintenance of long-term depression in the CA1 region of freely moving rats.
J. Neurosci. 20: 8572-8576.

Manahan-Vaughan, D. (2000)
Long-term depression in freely moving rats is dependent upon strain variation, induction protocol and behavioral state.
Cerebral Cortex 10: 482-487.

Kulla, A. and Manahan-Vaughan, D (2000)
Dopamine D1 receptors modulate depotentiation in the dentate gyrus of freely moving rats.
Cerebral Cortex 10: 614-620.

Manahan-Vaughan, D. (2000)
Group III metabotropic glutamate receptors modulate long-term depression in the hippocampal CA1 region of freely moving rats.
Neuropharmacology39: 1952-1958.

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Spilker C, K Richter, Smalla KH, Manahan-Vaughan D, Gundelfinger ED, Braunewell KH (2000)
The neuronal ef-hand calcium-binding protein visinin-like protein-3 is expressed in cerebellar purkinje cells and shows a calcium-dependent membrane association.
Neuroscience 96: 121 -129

Manahan-Vaughan, D. and Braunewell KH. (1999)
Novelty acquisition is associated with induction of hippocampal long-term depression.
Proc. Natl. Acad. Sci. USA 96: 8739-8744.

Manahan-Vaughan, D., Herrero I., Reymann, K.G. and Sanchez-Prieto, J. (1999)
Characterisation of pre- and post-synaptic modulation of LTP by group 1 metabotropic glutamate receptors.
Neuroscience 94: 71-82.

Kulla, A., Reymann K.G. and Manahan-Vaughan, D (1999)
Involvement of group 2 metabotropic glutamate receptors in hippocampal depotentiation in freely moving rats.
Eur. J. Neurosci. 11: 3864-72.

Balschun, D., Manahan-Vaughan, D., Wagner, T., Behnisch, T., Reymann, K. G., Wetzel, W. (1999)
A Specific Role for Group I mGluRs in Hippocampal LTP and Hippocampus-Dependent Spatial Learning. Learn. Mem. 6: 138-152

Manahan-Vaughan, D., Behnisch, T. and Reymann, K.G. (1999)
ACPD-mediated slow-onset potentiation in the hippocampus in vivo is associated with cell death.
Neuropharmacology 38: 487-494.

Manahan-Vaughan, D., (1998)
Priming of group 2 metabotropic glutamate receptors facilitates induction of long-term depression in the dentate gyrus of freely moving rats.
Neuropharmacology 37: 1459-1464.

Nakic, M., Manahan-Vaughan, D Reymann, K.G. and Schachner, M. (1998)
Long-term potentiation in vivo increases rat hippocampal Tenascin-C expression in vivo
J. Neurobiol. 37: 393-404.

Manahan-Vaughan, D., Braunewell K.H. and Reymann, K.G. (1998)
Subtype-specific involvement of metabotropic glutamate receptors in two forms of long-term potentiation in the dentate gyrus of freely moving rats.
Neuroscience 86, 709-721.

Manahan-Vaughan, D, Behnisch, T., Behnisch, G., Vieweg, S. and Reymann, K.G. (1998)
Semi-automated analysis of live/dead neurones in digitised colour images from rat hippocampal thin slices.
J. Neurosci. Meth. 82, 85-95

Manahan-Vaughan, D., Reymann, K.G. and Brown, R.E. (1998)
In vivo electrophysiological investigations into the role of histamine in the dentate gyrus of the rat.
Neuroscience 84, 783-790.

Manahan-Vaughan, D., (1997)
Group 1 and 2 metabotropic glutamate receptors play differential roles in hippocampal long-term depression and long-term potentiation in freely moving rats.
J. Neuroscience 17, 3293-3302.

Manahan-Vaughan, D., and Reymann, K.G. (1997)
Group 1 metabotropic glutamate receptors contribute to slow-onset potentiation in the rat CA1 region in vivo:
Neuropharmacology 36, 1533-1538

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Manahan-Vaughan, D., and Reymann, K.G. (1996)
Metabotropic glutamate receptor subtype agonists facilitate LTP within a distinct time window in the dentate gyrus in vivo.
Neuroscience 74, 723-731.

Manahan-Vaughan D., Reiser M., Pin J.P., Wilsch V., Reymann K.G and Riedel G. (1996)
Physiological and pharmacological profile of trans-azetidine 2,4-dicarboxylic acid: metabotropic glutamate receptor agonism and effects on long-term potentiation.
Neuroscience 72, 999-1008.

Manahan-Vaughan D, Anwyl R, Rowan MJ. (1995)
The azapirone metabolite 1-(2-pyrimidinyl)piperazine depresses excitatory synaptic transmission in the hippocampus of the alert rat via 5-HT1A receptors.
Eur J Pharmacol. 94(2-3):617-624.

Manahan-Vaughan D, Reymann KG. (1995)
1S,3R-ACPD dose dependently induces a slow onset potentiation in the dentate gyrus in vivo.
Eur J Pharmacol. 294(2-3):497-503.

Manahan-Vaughan D, Reymann KG. (1995)
Regional and developmental profile of modulation of hippocampal synaptic transmission and LTP by AP4-sensitive mGluRs in vivo.
Neuropharmacology. 34(8):991-1001.

Riedel G, Manahan-Vaughan D, Kozikowski AP, Reymann KG. (1995)
Metabotropic glutamate receptor agonist trans-azetidine-2,4-dicarboxylic acid facilitates maintenance of LTP in the dentate gyrus in vivo.
Neuropharmacology. 34(8):1107-9.

Manahan-Vaughan D, Reymann KG. (1995)
1S,3R-ACPD dose-dependently induces a slow-onset potentiation in the rat hippocampal CA1 region in vivo.
Neuropharmacology. 34(8):1103-1105.

Manahan-Vaughan D, Anwyl R, Rowan MJ. (1994)
5-HT1A receptor-mediated inhibition in the hippocampus of the alert rat--effects of repeated gepirone treatment.
Eur J Pharmacol. 260(2-3):149-155.

Manahan-Vaughan D, Anwyl R, Rowan MJ. (1994)
Adaptive changes in 5-HT1A receptor-mediated hippocampal inhibition in the alert rat produced by repeated 8-OH-DPAT treatment.
Br J Pharmacol. 112(4):1083-1088.

Book articles:
Manahan-Vaughan, D. (2005) Hippocampal long-term depression as a deckarative memory mechanism. In: Synaptic plasticity and transsynaptic signaling. New York: Springer.Ed: PK Stanton et al.

Manahan-Vaughan, D. (2001) The role of metabotropic glutamate receptors in hippocampal long-term depression and depotentiation in vivo. In: Excitatory Amino Acids: Ten Years later. IOS Press. Ed: E.A. Cavalheiro et al.

Manahan-Vaughan, D  and Reymann, K.G. (1998) Metabotropic glutamate receptors and hippocampal synaptic plasticity in vivo. In ‘Metabotropic Glutamate Receptors and Brain Function’, F. Moroni, F. Nicoletti and D.E. Pellegrini-Giampietro,eds. Portland Press, London. p 147-169.

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