Ruhr-Universität Bochum
Fakultät für Maschinenbau
Ruhr-Universität Bochum
D-44780 Bochum
Summary/Abstract
Project
C6 deals with the biocompatibility and
biofunctionalization of NiTi shape memory alloys (NiTi-SMA)
in the field of biomaterials and medical devices. In the
current period the application of material libraries for
biocompatibility screenings will be developed. To
determine optimal NiTi-SMA surfaces for orthopaedic
implants, adhesion and proliferation of tissue cells on
macro-, micro-and nanostructured NiTi-SMA surfaces will
be investigated. Additionally, studies on bio-corrosion
of NiTi-SMA induced by osteoclasts will be performed.
The analysis of cells cultivated on NiTi-SMA tensile
specimens under mechanical load is continued. Now that
methods have been established nickel reactive
lymphocytes from nickel allergic patients will be
applied to study different macro-, micro- and
nanostructured NiTi-SMA surfaces.
