Unlike conventional light-controllable proteins, the newly characterized optogenetic tool can be switched off, not switched on, by light. It could be suitable for investigating the basic principles of epilepsy.
(Picture: Some of the Bochum researchers: Melanie Mark, Johanna Pakusch, Jan Claudius Schwitalla, Stefan Herlitze, Ida Siveke)
This recorded interview is the third in our Interviews with Experts series and features Stefan Herlitze, PhD, Neuroscientist and Faculty of Biology and Biotechnology at Ruhr-Universität Bochum, Germany.
In order for the egg and sperm cells of corals from different colonies to intermingle, the individuals of one species must spawn at the same time. But how do they manage to synchronise it?
(Picture: Mareike Huhn during one of her dives. With the help of a magnifying glass, she tries to identify the coral species more closely.
Yang YM, Fekete A, Arsenault J, Sengar AS, Aitoubah J, Grande G, Li A, Salter EW, Wang A, Mark MD, Herlitze S, Egan SE, Salter MW, Wang LY (2024)
Intersectin-1 enhances calcium-dependent replenishment of the readily releasable pool of synaptic vesicles during development.
J Physiol. 2024 Oct 9. doi: 10.1113/JP286462. Online ahead of print. PMID: 39383250
Abstract
Barzan R, Bozkurt B, Nejad MM, Süß ST, Surdin T, Böke H, Spoida K, Azimi Z, Grömmke M, Eickelbeck D, Mark MD, Rohr L, Siveke I, Cheng S, Herlitze S, Jancke D. (2024)
Gain control of sensory input across polysynaptic circuitries in mouse visual cortex by a single G protein-coupled receptor type (5-HT2A).
Nat Commun. 2024 Sep 14;15(1):8078. doi: 10.1038/s41467-024-51861-1.
Abstract
Huhn M, Mark MD, Fiege A, Herlitze S (2024)
Native versus non-native ascidians in the Adriatic Sea: Species-specific patterns in behavior and HSP70 response during heat stress.
J. of Thermal Biol. 123: 103928.
Bihorac J, Salem Y, Dombrowski K, Lückemann L, Schedlowski M, Doenlen R, Engler H, Mark MD, Spoida K, Hadamitzky M (2024)
Investigations on the ability of the insular cortex to process peripheral immunosuppression.
Journal of Neuroimmune Pharmacology. Jul 30; 19(1):40.
Batsikadze G*, Pakusch J*, Klein M, Ernst TM, Thieme A, Nicksirat SA, Steiner KM, Nio E, Genc E, Maderwald S, Deuschl C, Merz CJ, Quick HH, Mark MD*, Timmann D* (2024)
Mild deficits in fear learning: Evidence from humans and mice with cerebellar cortical degeneration.
eNeuro. 2024 Jan 4:ENEURO.0365-23.2023. doi: 10.1523/ENEURO.0365-23.2023. Online ahead of print.
*Equal contribution.
Abstract
Krause F, Schmidtke K, de Vasconcelos MF, Schmidt D, Cansiz B, Theisen F, Mark MD, Rybarski MO.
A shedding analysis after AAV8 CNS injection revealed fragmented viral DNA without evidence of functional AAV particles in mice.
Gene Ther. 2024 Mar 12. doi: 10.1038/s41434-024-00447-z. Epub ahead of print.
Deane KE, Klymentiev R, Heck J, Mark MD, Ohl FW, Heine M, Happel MFK (2024)
Inhibiting presynaptic calcium channel motility in the auditory cortex suppresses synchronized input processing.
Front. Cell. Neurosci., 10 April 2024 Sec. Cellular Neurophysiology Volume 18 – 2024
doi: 10.3389/fncel.2024.1369047
Article
Piotrowski D, Clemensson EKH, Nguyen HP, Mark MD (2024)
Phenotypic analysis of ataxiain spinocerebellar ataxia type 6 mice using DeepLabCut.
Scientific Reports 14, 8571 (2024)
doi: 10.1038/s41598-024-59187-0
Article
Rybarski M, Mrohs D, Osenberg K, Hemmersbach M, Pfeffel K, Steinkamp J, Schmidt D, Violou K, Schäning R, Schmidtke K, Bader V, Andriske M, Bohne P, Mark MD, Winklhofer KF, Lübbert H, Zhu X-R (2023)
Loss of parkin causes endoplasmic reticulum calcium dyshomeostasis by upregulation of reticulocalbin 1.
Eur J Neurosci 2023 Mar;57(5):739-761. doi: 10.1111/ejn.15917. Epub 2023 Feb 3.
Abstract
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Last update: Oct 21, 2024
